This dataset describes 17 experimental runs for the production of silica nanomaterials via flame spray pyrolysis (FSP) from tetraethyl orthosilicate (TEOS, pure, Merck KGaA, Germany) in reagent alcohol (C2H5OH + CH3OH 94.0-96.0%, C3H8O 4.0-6.0%, VWR Chemicals BDH, USA). The dataset principally contains the various gas and liquid flowrates and the scanning mobility particle sizer outputs including particle counts for different diameter bins. Finally, the dataset contains the calculated statistics of the measured particle size distribution for each experimental run. See the following article for further details: https://doi.org/10.1016/j.matdes.2020.108972.